Is there Relationship between Parkinson’s Diseases and Mitochondria? – Parkinson’s Diseases 5

Illustration for simple mitochondria anatomy and physiology

(credit to MEME)

Mitochondria is organelles inside the most living cells, important to the cell since its has critical functions:

- to break down the nutrient into energy, then use or store its. Thus mitochondria is a kind of cell powerhouse.

- to process cell respiration

Disorder or dead of mitochondria could lead to dead of cells, then cause problems to organs, tissues or specific cells.

It is believed that mitochondria dysfunction may relate to many diseases, include:

- Parkinson's disease

- Alzheimer's disease

- heart disease

- diabetes

- muscle weakness

- Seizure

- Huntington’s diseases

- amyotrophic lateral sclerosis

Mechanism in mitochondria dysfunction, illustration only

(credit to frontiersin.org)

From my previous posts:

- Why People Could Get Parkinson’s Diseases? - Parkinson’s Diseases 1

- How Neuron Cells Affect on Parkinson’s Diseases? - Parkinson’s Diseases 2

We may summarize that:

1) “Neurons are brain cells.”

2) One of Neuron functions is to control our physical movement and balance

3) “These brain cells may die that affect on decreasing of dopamine, consequently, lead to movement disorders such as Parkinson’s diseases.”

Then, what relationships between mitochondria, brain cells, dopamine and Parkinson’s diseases?

Brain cells are hungrier cells, they are very much depend on mitochondria as source of energy. Malfunction or dead of mitochondria, will cause dead of brain cells.

From above summary, no 3) will be happen. We may conclude that mitochondria and brain cells responsible to Parkinson’s diseases.